CircuLex S100A10 ELISA Kit

CircuLex S100A10 ELISA Kit.

Specifications:

Components

  • Microplate
  • 10X Wash Buffer
  • Dilution Buffer
  • S100A10 Standard
  • HRP conjugated Detection Antibody
  • Substrate Reagent
  • Stop Solution

Description

This kit is used for the quantitative measurement of S100A10 in cell lysate, cell culture supernatant, serum, plasma and other biological media. It can be used for 96 Assays.

Target: S100A10
Product Type: ELISA Kit
Size: 96 Assays
Application: ELISA
Research Area / Disease: Immunology, Neuroscience
Sensitivity: better than 82.6 pg/ml of sample.
Measurement Range: 0.188 ng/mL to 12 ng/mL
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

References

  1. Donato, R.; S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. (2001) Int. J. Biochem. Cell Biol. 33, 637-668
  2. Gerke V, Moss SE.; Annexins: from structure to function. (2002) Physiol. Rev. 82, 331-371
  3. Girard, C. et al.; p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1. (2002) EMBO J. 21, 4439-4448
  4. Okuse, K. et al.; Annexin II light chain regulates sensory neuron-specific sodium channel expression. (2002) Nature 417, 653-656
  5. Wu, T. et al.; P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2. (1997) J. Biol. Chem. 272, 17145-17153
  6. Balch, C. and Dedman, J. R.; Annexins II and V inhibit cell migration. (1997) Exp. Cell Res. 237, 259-263
  7. Falcone, D. J. et al.; Plasminogen-mediated matrix invasion and degradation by macrophages is dependent on surface expression of annexin II. (2001) Blood 97, 777-784
  8. Kassam, G. et al.; The role of annexin II tetramer in the activation of plasminogen. (1998) J. Biol. Chem. 273, 4790-4799
  9. Mai, J. et al.; Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells. (2000) J. Biol. Chem. 275, 12806-12812
  10. Kassam, G. et al.; The p11 subunit of the annexin II tetramer plays a key role in the stimulation of t-PA-dependent plasminogen activation. (1998) Biochemistry 37, 16958-16966
  11. Choi, K. S. et al.; p11 regulates extracellular plasmin production and invasiveness of HT1080 fibrosarcoma cells. (2003) FASEB J. 17, 235-246
  12. MacLeod, T. J. et al.; Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits: characterization of the interaction with tissue plasminogen activator, plasminogen, and plasmin. (2003) J. Biol. Chem. 278, 25577-25584
  13. Fogg, D. K et al.; The p11 subunit of annexin II heterotetramer is regulated by basic carboxypeptidase. (2002) Biochemistry 41, 4953–4961
  14. Ito, K. Arai, R. Nozawa et al.; S100A10 expression in thyroid neoplasms originating from the follicular epithelium: contribution to the aggressive characteristic of anaplastic carcinoma. (2007) Anticancer Res. 2679-26783.
  15. McKiernan E et al.; The role of S100 genes in breast cancer progression. (2011) Tumour Biol. 32, 441-450
Code CY-8095
Product Type ELISA Kit
Size 96 Assays
Application ELISA
Price
$593.74
Qty: