Products Research Area/Disease Metabolism CircuLex Human RBP4 ELISA Kit

CircuLex Human RBP4 ELISA Kit

CircuLex Human RBP4 ELISA Kit.

Specifications:

Description

The CycLex Research Product CircuLex Human RBP4 ELISA Kit is used for the quantitative measurement of Human Retinol Binding Protein 4 (RBP4) in serum, plasma and other biological media. It can be used for 96 Assays.

Target:	RBP4
Product Type:	ELISA Kit
Size:	96 Assays
Application:	ELISA
Research Area / Disease:	Metabolism
Species Reactivity:	Human
Sensitivity:	better than 1.08 ng/mL of sample.
Measurement Range:	Dilution factors need to be taken into consideration in calculating the Human RBP4 concentration. Results exceeding diluted Human RBP4 level of 100 ng/ml should be repeated with diluted samples.
Regulatory Statement:	For Research Use Only. Not for use in diagnostic procedures.

Components

Microplate
10X Wash Buffer
Dilution Buffer
Human NGAL Standard
HRP conjugated Detection Antibody
Substrate Reagent
Stop Solution

Citations

Kimura Y et al. Identification of candidate diagnostic serum biomarkers for Kawasaki disease using proteomic analysis. Sci Rep. 7, 43732 (2017)

References

Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, et al. : Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. : Nature 436: 356–62, 2005
Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, et al. : Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab. 1: 107–119, 2005
Hotamisligil GS, Johnson RS, Distel RJ, Ellis R, Papaioannou VE, Spiegelman BM. : Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274: 1377–9, 1996
Wang Y, Lam KS, Kraegen EW, Sweeney G, Zhang J, Tso AW, Chow WS, Wat NM, Xu JY, Hoo RL, Xu A. : Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clin. Chem. 53: 34-41, 2007
van Dam RM, Hu FB. : Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2? Clin. Chem. 53: 5-7, 2007
Graham, T. E.; Yang, Q.; Bluher, M.; Hammarstedt, A.; Ciaraldi, T. P.; Henry, R. R.; Wason, C. J.; Oberbach, A.; Jansson, P.-A.; Smith, U.; Kahn, B. B.: Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. New Eng. J. Med. 354: 2552-2563, 2006.
Cho YM, Youn BS, Lee H, Lee N, Min SS, Kwak SH, Lee HK, Park KS.: Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes. Diabetes Care. 29: 2457-61, 2006
Haider DG, Schindler K, Prager G, Bohdjalian A, Luger A, Wolzt M, Ludvik B. Serum retinol-binding protein-4 is reduced after weight loss in morbidly obese subjects. J Clin Endocrinol Metab. 2006 Dec 12