Products Research Area/Disease Metabolism CircuLex Anti-CML Human autoAntibody ELISA Kit

CircuLex Anti-CML Human autoAntibody ELISA Kit (Discontinued)

CircuLex Anti-CML Human autoAntibody ELISA Kit.

Specifications:

Description

We are sorry for the inconvenience; this product code has been discontinued.

The CircuLex Anti-CML human autoantibody ELISA Kit is used for the semi-quantitative measurement of IgG class anti-CML/Nε-(carboxymethyl) lysine human autoantibody in human serum and plasma. It can be used for 96 Assays.

Target:	CML
Product Type:	ELISA Kit
Size:	96 Assays
Application:	ELISA
Research Area / Disease:	Metabolism
Species Reactivity:	Human
Sensitivity:	better than 0.32 ng/mL of sample.
Measurement Range:	Dilution factors need to be taken into consideration in calculating the antitoCML antibody concentration. Results exceeding antitoCMLtoautoantibody level of 2000 ng/ml, the sample should be repeated with dilution buffer.
Regulatory Statement:	For Research Use Only. Not for use in diagnostic procedures.

Components

Microplate
10X Wash Buffer
Dilution Buffer
Mouse Visfatin/PBEF Standard
HRP conjugated Detection Antibody
Substrate Reagent
Stop Solution

Citations

Koutroumani N et al. Protective mechanisms against oxidative stress and angiopathy in young patients with diabetes type 1 (DM1). 26, 309-17 (2013),
Meloche J, et al., RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. Arterioscler Thromb Vasc Biol. 31, 2114-2124 (2011)

References

Ikeda K, Higashi T, Sano H, Jinnouchi Y, Yoshida M, Araki T, Ueda S, Horiuchi S: Biochemistry 35: 8075 –8083,1996
Reddy S, Bichler J, Wells-Knecht KJ, Thorpe SR, Baynes JW: Biochemistry 34: 10872 –10878,1995
Makino H, Shikata K, Hironaka K, Kushiro M, Yamasaki Y, Sugimoto H, Ota Z, Araki N, Horiuchi S: Kidney Int 48: 517 –526,1995
Suzuki D, Yagame M, Jinde K, Naka R, Yano N, Endoh M, Kaneshige H, Nomoto Y, Sakai H: J Diabetes Complications 10: 314 –319,1996
Imai N, Nishi S, Suzuki Y, Karasawa R, Ueno M, Shimada H, Kawashima S, Nakamaru T, Miyakawa Y, Araki N, Horiuchi S, Gejyo F, Arakawa M: Nephron 76: 153 –160,1997
Murata T, Nagai R, Ishibashi T, Inomuta H, Ikeda K, Horiuchi S: Diabetologia 40: 764 –769,1997
Kume S, Takeya M, Mori T, Araki N, Suzuki H, Horiuchi S, Kodama T, Miyauchi Y, Takahashi K: Am J Pathol. 147: 654 –667,1995
Sakata N, Imanaga Y, Meng J, Tachikawa Y, Takebayashi S, Nagai R, Horiuchi S, Itabe H, Takano T: Atherosclerosis 141: 61 –75,1998
Sakata N, Imanaga Y, Meng J, Tachikawa Y, Takebayashi S, Nagai R, Horiuchi S: Atherosclerosis 142: 67 –77,1999
Kislinger T, Fu C, Huber B, Qu W, Taguichi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D, Schmidt AM: J Biol Chem 274: 31740 –31749,1999
Shibayama R, Araki N, Nagai R, Horiuchi S.; Autoantibody against N(epsilon)-(carboxymethyl)lysine: an advanced glycation end product of the Maillard reaction. Diabetes. 1999 Sep;48(9):1842-9.
Vay D, Vidali M, Allochis G, Cusaro C, Rolla R, Mottaran E, Bellomo G, Albano E.; Antibodies against advanced glycation end product Nepsilon-(carboxymethyl)lysine in healthy controls and diabetic patients. Diabetologia. 2000 Nov;43(11):1385-8.

Code	CY-8068
Product Type	ELISA Kit
Size	96 Assays
Application	ELISA
Price Call for Price