CycLex® Total p62 ELISA Kit

  • Applications
    • ELISA
  • Target Total p62
  • Code # CY-7055
  • Size 96 Assay
  • Price
    $618.80
Specifications

Alternative Names

sequestosome 1, p60, p62, A170, OSIL, PDB3, ZIP3, p62B/Osi, A170, STAP, OSF-6/Osi, ZIP

Background

The sequstosome1, p62/SQSTM1, is composed of multiple domain, which is Phox/Bem domain1, ZZ-type zinc finger domain, TRAF6 binding domain, LC3-intoracting region (LIR) motif, Keap1-interacting region (KIR), and ubiquitin-associated domain (UBA). Thus p62 plays a multifunctional scaffold protein that organize signal transduction and protein traffic. Additionally, binding to the autophagy regulator Atg8/LC3 through LIR motif and to the polyubiquitinated proteins through UBA domain, p62 is an important mediator for targeting polyubiquitinated proteins to the autophagic degradation system and p62 has a crucial role in the removal of aggregated proteins that are poorly degraded by proteasomes.
  • Application:
    ELISA
  • Description:
    The MBL Research Product CycLex Total p62 ELISA Kit is used for the quantitative measurement of human or mouse p62 protein in cell lysate.
  • Product Type:
    ELISA Kit
  • Sensitivity:
    0.154 ng/mL~
  • Size:
    96 Assay
  • Storage Temperature:
    4°C
  • Target:
    Total p62