CycLex® Cdc25C Protein Phosphatase Fluorometric Assay Kit

CycLex Cdc25C Protein Phosphatase Fluorometric Assay Kit.

Specifications:

Description

The CycLex Cdc25C Combo Fluorometric Assay Kit is a fluorometric and non-radioactive assay designed to measure the activity of Cdc25C protein phosphatase It can be used for 100 assays.

Target: CDC25C
Product Type: Kit
Size: 100 Assays
Research Area / Disease: Cancer
Storage Temperature: -20°C. Please refer to datasheet for additional information
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Components

  • 10x Assay Buffer
  • 10x 3-o-methyl fluorescein phosphate (OMFP)
  • Recombinant Human Cdc25C
  • 100x Cdc25 Inhibitor
  • Stop Solution

Citations

  1. Ajeawung NF et al. Investigation of Targetin, a Microtubule Binding Agent which Regresses the Growth of Pediatric High and Low Grade Gliomas. J Pediatr Oncol. 1, 32-40 (2013)
    1. Zhang S et al. Shikonin inhibits cancer cell cycling by targeting Cdc25s. BMC Cancer. 19, 20 (2019)rn

    References

    1. Morgan, D. O. (1997) Annu. Rev. Cell Dev. Biol. 13, 261-291
    2. Jinno, S., Suto, K., Nagata, A., Igarashi, M., Kanaoka, Y., Nojima, H., and Okayama, H. (1994) EMBO J. 13, 1549-1556 3. Hoffmann, I., Draetta, G., and Karsenti, E. (1994) EMBO J. 13, 4302-4310
    3. Nagata, A., Igarashi, M., Jinno, S., Suto, K., and Okayama, H. (1991) New Biol. 3, 959-968
    4. Karlsson, C., Katich, S., Hagting, A., Hoffmann, I., and Pines, J. (1999) J. Cell Biol. 146, 573-583
    5. Hoffmann, I., Clarke, P. R., Marcote, M. J., Karsenti, E., and Draetta, G. (1993) EMBO J. 12, 53-63
    6. Furnari, B., Rhind, N., and Russell, P. (1997) Science 277, 1495-1497
    7. Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H., and Elledge, S. J. (1997) Science 277, 1497-1501
    8. Peng, C.-Y., Graves, P. R., Thoma, R. S., Wu, Z., Shaw, A. S., and Piwnica-Worms, H. (1997) Science 277, 1501-1505
    9. Galaktionov, K., Lee, A. K., Eckstein, J., Draetta, G., Meckler, J., Loda, M., and Beach, D. (1995)
    10. Science 269, 1575-1577
    Code CY-1354
    Product Type Kit
    Size 100 Assays
    Price
    $548.48
    Qty: