CycLex® p38 Kinase Assay/Inhibitor Screening Kit
CycLex p38 Kinase Assay/Inhibitor Screening Kit.


Specifications:
Description
CycLex p38 Kinase Assay/Inhibitor Screening Kit.
Target: | p38 |
---|---|
Product Type: | Kinase Assay Kit |
Size: | 96 Assays |
Research Area / Disease: | Cell Biology |
Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Components
- Microplate
- 10X Wash Buffer
- Kinase Buffer
- 20X ATP
- Anti-Phospho-ATF2 Thr71 Polyclonal Antibody (PPT-08)
- HRP conjugated Anti-rabbit IgG
- Substrate Reagent
- Stop Solution
Citations
- Lin S et al. Auraptene suppresses inflammatory responses in activated RAW264 macrophages by inhibiting p38 mitogen-activated protein kinase activation. Mol Nutr Food Res. 57, 1135-44 (2013)
References
- English J, Pearson G, Wilsbacher J, et al. New insights into the control of MAP kinase pathways. Exp Cell Res. 1999; 253: 255-270.
- Dong C, Davis RJ, Flavell RA. MAP kinases in the immune response. Annu. Rev. Immunol. 2002; 20: 55-72
- Han J, Lee JD, Bibbs L, Ulevitch RJ. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science. 1994; 265: 808-811
- Chan-Hui, P. Y. and Weaver, R. (1998). Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascades. Biochem. J. 336,599 -609
- Stein B, Yand MX, Young DB, et al. p38–2, a novel mitogen-activated protein kinase with distinct properties. J Biol Chem. 1997; 272: 19509-19517
- Jiang Y, Chen C, Lie Z, et al. Characterization of the structure and function of a new mitogen-activated protein kinase (p38β). J Biol Chem. 1996; 271: 17920-179267) 7) Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 1997; 9:180-186.
- Enslen H, Raingeaud J, Davis RJ. Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem. 1998; 273: 1741-1748
- Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature. 1994; 372: 739-746