CycLex® Aurora-A kinase Assay/Inhibitor Screening Kit

CycLex Aurora-A kinase Assay/Inhibitor Screening Kit.

Specifications:

Description

The Aurora-A kinase Assay/Inhibitor Screening Kit is designed to measure the activity of purified Aurora-A and for the rapid and sensitive evaluation of inhibitors or activators of Aurora-A. It can be used for 96 assays.

Target: Aurora-A
Product Type: Kinase Assay Kit
Size: 96 Assays
Research Area / Disease: Cell Biology
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Components

  • Microplate (coated with recombinant Lats2-N-ter as an Aurora-A substrate)
  • 0X Wash Buffer
  • Kinase Buffer, 20X ATP
  • Anti-Phospho-Lats2-S83 Monoclonal Antibody (ST-3B11)
  • HRP-conjugated Anti-mouse IgG
  • Substrate Reagent
  • Stop Solution

 

Citations

  1. Mergen M et al. The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly. Nephrol Dial Transplant. 28, 2744-53 (2013)

References

  1. Zhou, H., Kuang, J., Zhong, L., Kuo, W. L., Gray, J. W., Sahin, A., Brinkley, B. R., and Sen, S. Nat. Genet. 20, 189-193, 1998
  2. Bischoff, J. R., Anderson, L., Zhu, Y., Mossie, K., Ng, L., Souza, B., Schryver, B., Flanagan, P.,
  3. Clairvoyant, F., Ginther, C., Chan, C. S., Novotny, M., Slamon, D. J., and Plowman, G. D. EMBO J. 17, 3052-3065, 1998
  4. Glover, D. M., Leibowitz, M. H., McLean, D. A., and Parry, H. Cell 81, 95-105, 1995
  5. Chan, C. S., and Botstein, D. Genetics 135, 677-691, 1993
  6. Glover, D..Mol.Cell. 12(4):797-9, 2003
Code CY-1165
Product Type Kinase Assay Kit
Size 96 Assays
Price
$654.60
Qty: