CycLex® Cellular Histone Acetylation Assay Kit
CycLex Cellular Histone Acetylation Assay Kit.
Specifications:
Description
The CycLex Cellular Histone Acetylation Assay Kit is used for the semi-quantitative measurement of histone acetylation level in situ by means of cell-based ELISA It can be used for 2 x 96 wells.
| Target: | Cellular Histone Acetylation |
|---|---|
| Product Type: | Kit |
| Size: | 2 x 96 Wells |
| Research Area / Disease: | Cancer |
| Storage Temperature: | 4°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Components
- Microplate
- 100X Trichostatin A
- 10X Wash Buffer
- Blocking Reagent
- Primary Antibody Solution(Anti-Acetylated Histone/p53-K382 Monoclonal Antibody TM-5C5)
- Secondary Antibody Solution (HRP conjugated Anti-Mouse IgG)
- Substrate Reagent, Stop Solution
Citations
- Okabe, Seiichi, Yuko Tanaka, and Akihiko Gotoh. “Targeting phosphoinositide 3-kinases and histone deacetylases in multiple myeloma.” Experimental Hematology & Oncology 10.1 (2021): 1-12.
- Okabe, Seiichi, et al. “Effect of dual inhibition of histone deacetylase and phosphatidylinositol-3 kinase in Philadelphia chromosome-positive leukemia cells.” Cancer Chemotherapy and Pharmacology 85.2 (2020): 401-412.
- Shan, Changliang, et al. “4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis.” Cell death & disease 10.7 (2019): 1-13.
- Nishino T, Wang C, Mochizuki-Kashio M, Osawa M, Nakauchi H, Iwama A.; Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase. PLoS One. 6:e24298. 2011,
- K Reed , S L Hembruff , J A Sprowl & A M Parissenti; The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance. The Pharmacogenomics Journal, 10: 489-504, 2010,
References
- Davie, J. R & Chadee, D. N. J. Cell Biochem. (Suppl.) 30-31, 203-213, 1998
- Kouzarides, T. Curr. Opin. Genet. Dev. 9, 40-84, 1999
- Fenrick, R. & Hiebert, S.W. J. Cell Biochem. (Suppl.) 30-31, 194-202, 1998
- Yoshida, M., Horinouchi, S. & Beppu, T. Bioassays 17, 423-430, 1995
- Richon, V. M. et al. Proc. Natl. Acad. Sci. USA 93, 5705-5708, 1996
- Richon, V. M. et al. Proc. Natl. Acad. Sci. USA 95 3003-3007, 1998
- Cohen, L. et al. Proc. AACR 39, 108, abstr. 736, 1998
- Desai, D., El-Bayoumy, K. & Amin, S. Proc. AACR 40, 2396, abstr. 362, 1999
- Laherty, C. D., Yang, W-M. et al Cell 89, 349-356, 1997
- Hassig, C., Fleischer, T. C. et al Cell 89, 341-347, 1997
- Hoffmann, K., Grosch, G. & Jung, M Nucleic Acids Res. 27, 2057-2058, 1999
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Brochures
Immuno-Oncology
