cycLex EphA2 Kinase Assay/Inhibitor Screening Kit-Discontinued

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This product has been discontinued.

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References

  1. Holder N., Klein R. Eph receptors and ephrins: effectors of morphogenesis. Development (Camb.), 126: 2033-2044, 1999.
  2. Dodelet V. C., Pasquale E. B. Eph receptors and ephrin ligands: embryogenesis to tumorigenesis. Oncogene, 19: 5614-5619, 2000
  3. Easty D. J., Herlyn M., Bennett D. C. Abnormal protein tyrosine kinase gene expression during melanoma progression and metastasis. Int. J. Cancer, 60: 129-136, 1995.
  4. Nemoto T., Ohashi K., Akashi T., Johnson J., Hirokawa K. Overexpression of protein tyrosine kinases in human esophageal cancer. Pathobiology, 65: 195-203, 1997.
  5. Rosenberg I. M., Goke M., Kanai M., Reinecker H. C., Podolsky D. K. Epithelial cell kinase-B61: an autocrine loop modulating intestinal epithelial migration and barrier function. Am. J. Physiol., 273: G824-G832, 1997.
  6. Zelinski D., Zantek N., Stewart J., Irizarry A., Kinch M. EphA2 overexpression causes tumorigenesis of mammary epithelial cells. Cancer Res., 61: 2301-2306, 2001.
  7. Walker-Daniels J., Coffman K., Azimi M., Rhim J. S., Bostwick D. G., Snyder P., Kerns B. J., Waters
  8. D. J., Kinch M. S. Overexpression of the EphA2 tyrosine kinase in prostate cancer. Prostate, 41: 275-280, 1999.
  9. Kinch M. S., Moore M. B., Harpole D. H., Jr. Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival. Clin. Cancer Res., 9: 613-618, 2003.
  10. Miyazaki T., Kato H., Fukuchi M., Nakajima M., Kuwano H. EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma. Int. J. Cancer, 103: 657-663, 2003.
  11. Miao H., Burnett E., Kinch M., Simon E., Wang B. Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation. Nat. Cell Biol., 2: 62-69, 2000.
  12. Dohn M., Jiang J., Chen X. Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis. Oncogene, 20: 6503-6515, 2001.
  13. Ogawa K., Pasqualini R., Lindberg R., Kain R., Freeman A., Pasquale E. The ephrin-A1 ligand and its receptor, EphA2 are expressed during tumor neovascularization. Oncogene, 19: 6043-6052, 2000.
  14. Hess A. R., Seftor E. A., Gardner L. M., Carles-Kinch K., Schneider G. B., Seftor R. E., Kinch M. S., Hendrix M. J. Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2). Cancer Res., 61: 3250-3255, 2001.
  15. Cheng N., Brantley D. M., Liu H., Lin Q., Enriquez M., Gale N., Yancopoulos G., Cerretti D. P., Daniel T. O., Chen J. Blockade of EphA receptor tyrosine kinase  ctivation inhibits vascular endothelial cell growth factor-induced angiogenesis. Mol. Cancer Res., 1: 2-11, 2002
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