Anti-SynCAM (TSLC1/CADM1) (Human) mAb

  • Applications
    • FCM
  • Target SynCAM/TSLC1
  • Host Species Chicken
  • Species Reactivities Human
  • Code # CM005-3
  • Size 100 μg
  • Price
    $389.88
Specifications

Background

SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts.
  • Antibody Type:
    Polyclonal
  • Application:
    FCM
  • Clone Number:
    9D2
  • Concentration:
    1 mg/mL
  • Conjugate:
    Unlabeled
  • Description:
    Monoclonal antibody of 100 μg targeting SynCAM/TSLC1 for FCM.
  • Formulation:
    1 mg/mL in PBS/50% glycerol, pH 7.2
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Chicken
  • Immunogen:
    Recombinant fusion protein SynCAM / Fc
  • Isotype:
    IgY
  • Product Type:
    Antibody
  • Reactivity:
    This antibody reacts with extracellular domain of SynCAM on Flow cytometry.
  • Research Area:
    Neuroscience
  • Short Description:
    SynCAM/TSLC1 Monoclonal Antibody.
  • Size:
    100 μg
  • Species Reactivity:
    Human
  • Storage Temperature:
    -20°C
  • Target:
    SynCAM/TSLC1
References
  1. Hollins, F., et al., J. Immunol. 181, 2772-2780 (2008)
  2. Yang, W., et al., J. Immunol. 176, 1238-1243 (2006)
  3. Furuno, T., et al., J. Immunol. 174, 6934-6942 (2005)
  4. Sara, Y., et al., J. Neuroscience 25, 260-270 (2005)
  5. Biederer, T., et al., Science 297, 1525-1531 (2002)