Coxsackie B Screen (each well contains a mixture of B1, B2, B3, B4, B5 and B6) Substrate Slide

  • Applications
    • IF
  • Code # CB-3306
  • Size 6 wells
  • Price Call for Price


Coxsackieviruses were first recovered in 1949 in suckling mice inoculated with the fecal extracts from two children with paralytic poliomyelitis-like syndrome. Currently, there are six Coxsackievirus B and twenty-four Coxsackievirus A serotypes recognized. The virus is spread primarily by fecal-oral contamination, although respiratory transmission also occurs. The virus initially colonizes the alimentary tract, growing in the lymphoid tissues of the nasopharynx and intestinal tract. Viremia subsequently occurs allowing secondary localization in other viscera and lymphoid tissues. Infection is often asymptomatic (30-90%), but a wide variety of notable syndromes may also occur such as paralytic disease, aseptic meningitis, encephalitis, pleurodynia, pericarditis, herpangina and lymphonodular pharyngitis. The most common clinical picture is that of an undifferentiated febrile illness with malaise, headache, myalgia and sore throat.

  • Application:
  • Components:
    MBL Bion COXSACKIEVIRUS B ANTIGEN SUBSTRATE SLIDES are individually foil-wrapped slides of six wells with a mixture of Coxsackievirus B (1-6; NIH strains) infected and uninfected A549 cells fixed onto each well. Each well contains an average on 20-30% infected cells per 200X field.
  • Description:

    The MBL Bion COXSACKIEVIRUS B ANTIGEN SUBSTRATE SLIDES may be utilized in the indirect fluorescent antibody assay. Each lot is tested with a panel of titered sera to ensure sensitivity lot to lot; both positive and negative cells are in each well to provide a built-in control.


    The MBL Bion COXSACKIEVIRUS B ANTIGEN SUBSTRATE SLIDES may be used as the antigenic substrate in indirect fluorescent antibody assays for the qualitative and/or semi-quantitative determination of Coxsackievirus B antibodies in human serum. MBL Bion COXSACKIEVIRUS B ANTIGEN SUBSTRATE SLIDES are intended for use as an aid in the diagnosis of active infection and as a determination of immunological experience with Coxsackievirus B.

  • Product Type:
    Antigen Substrate Slide
  • Research Area:
    Infectious Disease
  • Short Description:

    The MBL Bion COXSACKIEVIRUS B ANTIGEN SUBSTRATE SLIDES may be used as the antigenic substrate in indirect fluorescent antibody assays for the qualitative and/or semi-quantitative determination of Coxsackievirus B antibodies in human serum. 

  • Size:
    6 wells
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