Caspase-1 Polyclonal Antibody

  • Applications
    • IHC
    • IP
    • WB
  • Target caspase-1
  • Species Reactivities Human, Mouse, Rat
  • Code # BV-3019-3
  • Size 100 µg
  • Price
    $357.92
Specifications

Alternative Names

CASP1, IL1BCE, P45, Interleukin-1 beta convertase, IL-1BC, IL1BC, p45, IL1B-convertase, CASP-1, ICE

Background

Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
  • Antibody Type:
    Polyclonal
  • Application:
    IHC, IP, WB
  • Concentration:
    0.2 mg/ml
  • Conjugate:
    Unlabeled
  • Description:
    caspase-1 Primary Antibody of 100 µg.
  • Product Type:
    Antibody
  • Research Area:
    Apoptosis
  • Short Description:
    caspase-1 Primary Antibody.
  • Size:
    100 µg
  • Species Reactivity:
    Human, Mouse, Rat
  • Storage Temperature:
    -20°C
  • Target:
    caspase-1