Apaf-1 Polyclonal

  • Applications
    • WB
  • Target Apaf1
  • Species Reactivities Bovine, Horse, Human, Monkey, Mouse, Rat
  • Code # BV-3018-3
  • Size 100 µg
  • Price
    $350.89
Specifications

Alternative Names

APAF1, CED4, DKFZp781B1145, KIAA0413

Background

During apoptosis, Apaf-1 (apoptosis protease activating factor 1) binds to cytochrome c (Apaf-2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro-caspase-9, and activates caspase-9 (Apaf-3). Activated caspase-9 in turn cleaves and activates caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf-1 is ubiquitously expressed in human tissues.
  • Antibody Type:
    Polyclonal
  • Application:
    WB
  • Concentration:
    0.2 mg/ml
  • Conjugate:
    Unlabeled
  • Description:
    Apaf1 Primary Antibody of 100 µg.
  • Product Type:
    Antibody
  • Research Area:
    Apoptosis
  • Short Description:
    Apaf1 Primary Antibody.
  • Size:
    100 µg
  • Species Reactivity:
    Bovine, Horse, Human, Monkey, Mouse, Rat
  • Storage Temperature:
    -20°C
  • Target:
    Apaf1