Anti-SLC17A9 isoform 2 (VNUT) (Human) pAb

  • Applications
    • FCM
    • IHC
  • Target SLC17A9 isoform2/VNUT
  • Host Species Rabbit
  • Species Reactivities Human
  • Code # BMP079
  • Size 100 μl
  • Price
    $306.33
Specifications

Background

Adenosine-5’-triphosphate (ATP), which is known to play an important role in intracellular energy transfer, also functions extracellularlly as a chemical transmitter in purinergic signal transmission in neurons and endocrine cells. ATP is stored in secretory vesicles and subsequently exocytosed to stimulate various purinergic responses including those of autonomic functions, pain and mechanosensory transduction, neural-glial interactions, as well as platelet aggregation. Solute carrier family 17 (SLC17) has been originally classified as the vesicular glutamate transporter family, but SLC17A9 isoform2/VNUT may play a role in the vesicular storage of ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles.
  • Antibody Type:
    Polyclonal
  • Application:
    FCM, IHC
  • Conjugate:
    Unlabeled
  • Description:
    Polyclonal antibody of 100 µl targeting SLC17A9 isoform2/VNUT for FCM, IHC.
  • Formulation:
    100 µl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rabbit
  • Immunogen:
    Synthetic peptide derived from human SLC17A9 isoform2
  • Isotype:
    IgG
  • Product Type:
    Antibody
  • Reactivity:
    This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including the small intestine and kidney by Immunohistochemistry. The reactivity has been confirmed by intracellular Flow cytometry to detect the full length of human
  • Research Area:
    Cell Biology
  • Short Description:
    SLC17A9 isorm2/VNUT Polyclonal Antibody.
  • Size:
    100 μl
  • Species Reactivity:
    Human
  • Storage Temperature:
    -20°C
  • Target:
    SLC17A9 isoform2/VNUT
Citations
  1. Chaudhury A et al., Role of myosin Va in purinergic vesicular neurotransmission in the gut. Am J Physiol Gastrointest Liver Physiol. 302, G598-607 (2012),
  2. Jung J et al., Possible ATP release through lysosomal exocytosis from primary sensory neurons. Biochem Biophys Res Commun. 430, 488-493 (2013),
  3. Shin YH et al., Secretion of ATP from Schwann cells through lysosomal exocytosis during Wallerian degeneration. Biochem Biophys Res Commun. 429, 163-167 (2012)
References
  1. Sawada, K., et al., PNAS 105, 5683-5686 (2008)
  2. Rudnick G., et al., PNAS 105, 5949-5950 (2008)