Anti-SLC16A2 (MCT8) (Human) pAb

  • Applications
    • FCM
    • ICC
    • IHC
    • WB
  • Target SLC16A2
  • Host Species Rabbit
  • Species Reactivities Human
  • Code # BMP031
  • Size 50 μl
  • Price
    $306.33
Specifications

Alternative Names

MCT8

Background

SLC16A2, also known as monocarboxylate transporter 8 (MCT8), is responsible for the transport of thyroid hormone 3 (T3) into the nerve cells in the developing brain. After T3 is transported into a nerve cell, it interacts with intranuc lear receptors, which activate or inhibit the expression of specific genes that are related to cell migration, dendrite formation, and synapse development. SLC16A2 is also distributed in several organs such as the liver, heart, brain, thymus, intestine, ovary, prostate, pancreas, and placenta. A mutation in the SLC16A2 gene inhibits the transport of T3 into the brain and results in the Allan-Herndon-Dudley syndrome, which is characterized by severe intellectual disability and impaired movement.
  • Antibody Type:
    Polyclonal
  • Application:
    FCM, ICC, IHC, WB
  • Conjugate:
    Unlabeled
  • Description:
    Polyclonal antibody of 50 μl targeting SLC16A2 for FCM, ICC, IHC, WB.
  • Formulation:
    50 µl volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rabbit
  • Immunogen:
    Synthetic peptide derived from human SLC16A2
  • Isotype:
    IgG
  • Product Type:
    Antibody
  • Reactivity:
    This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including the pancreas, cerebellum and small intestine by Immunohistochemistry. The reactivity has been confirmed by Western blotting, Im munocytochemistry, and intra
  • Research Area:
    Cell Biology
  • Short Description:
    SLC16A2 Polyclonal Antibody.
  • Size:
    50 μl
  • Species Reactivity:
    Human
  • Storage Temperature:
    -20°C
  • Target:
    SLC16A2
References
  1. Schwartz, C. E., et al., Am. J. Hum. Genet. 77, 41-53 (2005)
  2. Lafrenière, R. G., et al., Hum. Mol. Genet. 3, 1133-1139 (1994)