Anti-SLC6A2 (NET) (Human) pAb

  • Applications
    • FCM
    • ICC
    • IHC
    • WB
  • Target SLC6A2/NET
  • Host Species Rabbit
  • Species Reactivities Human
  • Code # BMP029
  • Size 50 μl
  • Price
    $306.33
Specifications

Background

SLC6A2, also known as NET, is a norepinephrine (noradrenaline) transporter, which regulates norepinephrine homeostasis by reuptaking the norepinephrine released into synaptic cleft in Na + - and Cl - - dependent manner. Mutation of the SLC6A2 gene can cause orthostatic intolerance, which is characterized by lightheadedness, fatigue, altered mental condition, and syncope. Drugs inhibiting the norepinephrine transporter such as antidepressants, cocaine, and amphetamines also lead to symptoms like orthostatic intolerance.
  • Antibody Type:
    Polyclonal
  • Application:
    FCM, ICC, IHC, WB
  • Conjugate:
    Unlabeled
  • Description:
    Polyclonal antibody of 50 μl targeting SLC6A2/NET for FCM, ICC, IHC, WB.
  • Formulation:
    50 µl volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rabbit
  • Immunogen:
    Synthetic peptide derived from human SLC6A2
  • Isotype:
    IgG
  • Product Type:
    Antibody
  • Reactivity:
    This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including the brain and liver by Immunohistochemistry. The reactivity has been confirmed by Western blotting, Immunocytochemistry, and intr acellular Flow cytometry t
  • Research Area:
    Cell Biology
  • Short Description:
    SLC6A2/NET Polyclonal Antibody.
  • Size:
    50 μl
  • Species Reactivity:
    Human
  • Storage Temperature:
    -20°C
  • Target:
    SLC6A2/NET
Citations
  1. Kim, C. H., et al., PNAS 103, 19164-19169 (2006)
  2. Paczkowski, F. A. et al., Pharmacogenetics 12, 165-173 (2002)
  3. Shannon, J. R., et al., New Eng. J. Med. 342, 541-549 (2000)
  4. Pacholczyk, T., et al., Nature 350, 350-354 (1991)
References
  1. Kim, C. H., et al., PNAS 103, 19164-19169 (2006)
  2. Paczkowski, F. A. et al., Pharmacogenetics 12, 165-173 (2002)
  3. Shannon, J. R., et al., New Eng. J. Med. 342, 541-549 (2000)
  4. Pacholczyk, T., et al., Nature 350, 350-354 (1991)