Anti-SLC7A9 (B0, +AT) (Human) pAb

  • Applications
    • FCM
    • ICC
    • IHC
    • WB
  • Target SLC7A9/B0 ,+AT
  • Host Species Rabbit
  • Species Reactivities Human
  • Code # BMP021
  • Size 50 μl
  • Price
    $306.33
Specifications

Background

SLC7A9, also known as B0,+- type amino acid transporter (B0,+AT), is a member of the cationic amino acid transporter/glycoprotein-associated family, and it functions as a heterodimer with the amino acid transport protein SLC3A1/rBAT. The SLC7A9 protein is predominantly distributed in the kidney, small intestine, liver, and placenta. Defective mutations in the SLC7A9 and/or SLC3A1 gene cause cystinuria, which is characterized by impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract; this results in the formation of calculi due to cystine precipitation in the urinary tract, leading to obstruction, infections, and ultimately, renal insufficiency.
  • Antibody Type:
    Polyclonal
  • Application:
    FCM, ICC, IHC, WB
  • Conjugate:
    Unlabeled
  • Description:
    Polyclonal antibody of 50 μL targeting SLC7A9/B0,+AT for FCM, ICC, IHC, WB.
  • Formulation:
    50 µl volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.
  • Gene ID (Human):
  • Host Species:
    Rabbit
  • Immunogen:
    Synthetic peptide derived from human SLC7A9
  • Isotype:
    IgG
  • Product Type:
    Antibody
  • Reactivity:
    This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including the small intestine and kidney by Immunohistochemistry. The reactivity has been confirmed by Western blotting, Immunocytochemistry and intracellular Flow cy
  • Research Area:
    Cell Biology
  • Short Description:
    SLC7A9/B0,+AT Polyclonal Antibody.
  • Size:
    50 μl
  • Species Reactivity:
    Human
  • Storage Temperature:
    -20°C
  • Target:
    SLC7A9/B0 ,+AT
References
  1. Eggermann, T., Hum Genet. 126, 330 (2009)
  2. Feliubadaló, L., et al., Hum. Mol. Genet. 12, 2097-2108 (2003)
  3. Leclerc, D., et al., Kidney Int. 62, 1550-1559 (2002)
  4. Colombo, R., Genomics 69, 131-134 (2000)
  5. Feliubadalo, L., et al., Nat. Genet. 23, 52-57 (1999)