Autophagy

Autophagy is a cellular self-digestion process for the purpose of providing nutrients to allow for cell survival during stress conditions. Autophagy can be selective (mitophagy) or non-selective (nutrient poor). Autophagy plays an important role in maintaining the cell homeostasis by removing non-essential cell components. Recent research has also shown an association of mammalian autophagy with pathological conditions including neurodegenerative diseases, infection, cardiac disease, cancer and aging.

Autophagy1

 

Antibodies against p62/SQSTM1

Autophagy2 

Detection of LC3 using PM036

 

 

 

 

Antibodies against p62/SQSTM1

auto2 

Detection of p62-positive inclusion bodies in the human hepatocellular carcinoma using PM045

 

 

Related Product Highlight

Keima-Red for mitophagy detection in living cells

Mitophagy is the process of selective mitochondrial degradation by autophagy. It has been found to be involved in neurodegenerative and cardiovascular diseases as well as cancer.

keima1

Related Products

Product Product Code Description
Autophagy Watch 8486 For Autophagy Flux Assay and LC3 Immunostaining.
Autophagy Ab Sampler Set 8485 Popular MBL antibodies for autophagy-related proteins are available in a set.

Learn more about other Autophagy targets and products

Atg12 Atg14 Atg16L Atg9 ULK1

Related Topic

Mitophagy

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