MEBSTAIN Apoptosis TUNEL Kit Direct

The MEBSTAIN Apoptosis TUNEL Kit Direct is intended for the detection of apoptotic cells in research samples.

Specifications:

Description

In cells in which apoptosis occurs, the chromatin DNA is cut by endonuclease at linker DNA site between nucleosomes. Then, DNA fragments, which are a number of multimers of nucleosomal units exit in nuclei. In TUNEL method, 3’-OH DNA ends generated by DNA fragmentation is nick end labeled with fluorescein-dUTP, mediated by terminal deoxynucleotidyl transferase (TdT). This method allows specific staining.

Target: Apoptosis
Product Type: Apoptosis Kit
Size: FCM:66 Tests, Stain: 40 Tests
Research Area / Disease: Apoptosis
Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Gao B et al. Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells. Stem Cell Res Ther. 9, 162 (2018)
  2. Kozako T et al. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. BMC Cancer. 18, 791 (2018)
  3. Tsuruta Y et al. Apoptosis induced by Ibaraki virus does not affect virus replication and cell death in hamster lung HmLu-1 cells. J Vet Med Sci. 81, 197-203 (2019)
  4. Kozako T et al. High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor. Eur J Pharmacol. 865, 172738 (2019)rn

References

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Code 8445
Product Type Apoptosis Kit
Size FCM:66 Tests, Stain: 40 Tests
Price
$459.00
Qty:

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