Anti-TRAF6 (Mouse) pAb

  • Applications
    • IP
    • WB
  • Target TRAF6
  • Host Species Rabbit
  • Species Reactivities Mouse
  • Code # 597
  • Size 100 µl
  • Price
    $278.49
Specifications

Background

The TRAF-C domain is involved in homotypic and heterotypic aggregation of TRAFs and in interaction of the TNF-receptor superfamily. TRAF6 cDNA has been identified as sequences homologous to the TRAF-C domain of TRAF2 and as binding the cytoplasmic tail of CD40 using the yeast two hybrid system. TRAF6 has a TRAF domain in its carboxyl terminus and has a RING finger domain, a cluster of zinc fingers and a coiled-coil domain. TRAF6 interacts strongly with itself, and weakly with both TRAF2 and TRAF3. Overexpression of TRAF6 activates NF-ĸB. TRAF6 is likely to be a component of the signaling cascade that starts at the IL-1β receptor and results in the activation of NF-ĸB.
  • Antibody Type:
    Polyclonal
  • Application:
    IP, WB
  • Conjugate:
    Unlabeled
  • Description:
    Polyclonal antibody of 100 µl targeting TRAF6 for WB, IPP.
  • Formulation:
    100 μg IgG in 100 μL volume of PBS containing 50% glycerol, pH 7.2. Contains no preservatives.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rabbit
  • Immunogen:
    Recombinant mouse terminal TRAF6 N (1-305 aa)
  • Isotype:
    IgG
  • Product Type:
    Antibody
  • Reactivity:
    Anti-TRAF6 antibody reacts with murine TRAF6 on Western blotting and immuno- precipitation. Does not cross-react with other TRAF family, TRAF1, TRAF2, TRAF3, TRAF4 and TRAF5. The antibody detects the 58 kDa TRAF6 on Western blotting using total cell lysat
  • Research Area:
    Cell Biology
  • Short Description:
    TRAF6 primary antibody.
  • Size:
    100 µl
  • Species Reactivity:
    Mouse
  • Storage Temperature:
    -20°C
  • Target:
    TRAF6
Citations
  1. Kato Y and Kaneko MK. Generation of a novel monoclonal antibody WMab-1 specific for IDH2-R172W mutation. Biochem Biophys Res Commun. 433, 374-8 (2013)
References
  1. Cao, Z., et al., Nature 383, 443-446 (1996)
  2. Ishida, T., et al., J. Biol. Chem. 271, 28745-28748 (1996)