Solutions for Life Science & Diagnostics
T-Select Mouse CD1d Tetramer-SA-PE
Additional Information
T-Select Mouse CD1d Tetramer-SA-PE Specifications
| Background: | Natural Killer T cells (NKT cell), a type of T cell that plays a significant role in immune response, produce a large quantity of INF-γ and IL-4 in response to phospholipids that present in CD1d molecules. In recent years, NKT are reported to play a part in diabetes and tumor immunity. Therefore, a technology allowing quantitative measurement of CD1d-positive NKT cells would be a useful tool for immunology and clinical laboratory examinations. In recent years, a flow cytometric method of measuring NKT cells specifically and quantitatively has been developed in which CD1d/phospholipid compound tetramer labeled by Phycoerythrin (PE) is used as a probe. T-Select Mouse CD1d Tetramer-SA-PE is a reagent created by tetramerizing biotinylated Mouse CD1d molecule with streptavidin labeled by phycoerythrin (PE). ï¡-galactosylceramide (ï¡-GalCer), a phospholipid separated and synthesized from sponge, combines with CD1d to activate human and mouse NKT cells. Thus it is possible to quantify human and mouse NKT cell populations by combining T-Select Mouse CD1d Tetramer-SA-PE with ï¡-GalCel. Measurement can be performed using isolated lymphocytes/monocytes. |
| Gene ID Human: | 912 |
| Gene ID Mouse: | 12479 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Kit |
| Shipping: | 4 |
| Size: | 10 tests |
| Status: | RUO |
| Storage: | 4 |
| Target: | T-Select Mouse CD1d Tetramer |
Applications:
There are no references for T-Select Mouse CD1d Tetramer-SA-PE at this time.
