Fas (CD95), Human

Datasheet:

SY-001.pdf

( Email this file )

Gene/antigen ID number:

355

Target:

Fas (CD95)

Background:

Apoptosis plays an important role in
the selection of immature thymocytes and Ag-primed
peripheral T cells. Fas antigen is a cell-surface protein that
mediates apoptosis. It is expressed in various tissues
including the thymus and has structural homology with a
number of cell-surface receptors, including tumor necrosis
factor receptor and nerve growth factor receptor.

Size:

100 µL

Application:

FCM

Application:

WB

Clone Number:

CH-11

Concentration:

500 Î¼g/mL

Conjugate:

affinity chromatography

Product Type:

Primary Antibody

Host Species:

Mouse

Species Reactivities:

Human

Species Reactivities:

Rat

Isotype:

IgM

Storage Temp. (°C):

-20

Shipping Temp. (°C):

4

Pictures:

Related Products:

MD-10-3 Anti-Human Fas (UB2)
MD-10-4 FITC labeled Anti-Human Fas (UB2)
MD-10-5 PE labeled Anti-Human Fas (UB2)
MD-11-3 Anti-Human Fas (ZB4)
D026-3 Anti-Mouse Fas (RMF2)
D027-3 Anti-Mouse Fas (RMF6)
D041-3 Anti-Human Fas Ligand (4H9)
D041-4 FITC labeled Anti-Human Fas Ligand (4H9)
D041-5 PE labeled Anti-Human Fas Ligand (4H9)
D041-6 Biotin labeled Anti-Human Fas Ligand (4H9)
D042-3 Anti-Human Fas Ligand (4A5)
D057-3 Anti-Mouse Fas Ligand (FLIM58)
D057-4 FITC labeled Anti-Mouse Fas Ligand (FLIM58)
D057-6 Biotin labeled Anti-Mouse Fas Ligand (FLIM58)
D069-3 Anti-Mouse Fas Ligand (FLIM4)

References:

1) Okamoto, K., et al., Genes Cells 11, 177-191 (2006)
2) Ohgushi, M., et al., Mol. Cell. Biol. 25, 10017-10028
(2005)
3) Kotone-Miyahara, Y., et al., J. Leukoc. Biol. 76,
1047-1056 (2004)
4) Lee, K-K., et al., J. Biol. Chem. 276, 19276-19285
(2001)
5) Ichikawa, K., et al., Int. Immunol. 12, 555-562 (2000)
6) Tsukumo, S. I., et al., Genes Cells 4, 541-549 (1999)
7) Yamashita, K., et al., Blood 93, 674-685 (1999)
8) Ito, N., et al., Cell 66, 233-243 (1991)
9) Kobayashi, N., et al., PNAS 87, 9620-9624 (1990)
10) Yonehara, S., et al., J. Exp. Med. 169, 1747-1756 (1989)
This antibody is used in these references.

Formulation:

50 μg IgM in 100 μL PBS containing 50% glycerol, pH 7.2. Contains no preservatives.

Reactivity:

This antibody induces apoptosis in human cell lines expressing Fas antigen.

Intended Use:

For Research use only. Not for use in diagnostic procedure.

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