ELAVL2/HuB is a neuron-specific RNA-binding protein, which contains three RNA-recognition motifs (RRMs) and was found to bind in vitro to the 3′ untranslated region (UTR) of Id mRNA encoding a transcriptional repressor, which is abundantly expressed in undifferentiated neural precursors. Overexpression of ELAVL2/HuB can result in increased stability and translation of the eag-related gene (ERG) mRNA, which bears a U-rich region in its 3′ UTR.