Angiogenesis
Apoptosis
Autophagy & Proteolysis
Cancer & Cell Proliferation
Cell Surface Antigens
Cellular Stress
Cytokines & Growth Factors
Epigenetics
Epitope Tags
Fluorescent Proteins
GPCR
In Vitro Diagnostics
Inflammation & Immunology
Metabolism
Molecular Biology
Neuroscience
Signal Transduction
Solute Carrier
Virology
Other
Product Catalog |
Atg5 polyclonal antibodyCode No: PM050
Target:
Atg5 Background:
Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg12-Atg5-Atg16L forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane.
Size:
100 μL
Application:
WB
Clone Number:
Polyclonal
Product Type:
Primary Antibody
Host Species:
Rabbit
Species Reactivities:
Human
Species Reactivities:
Mouse
Species Reactivities:
Rat
Isotype:
IgG (aff.)
Storage Temp. (°C):
-20
Shipping Temp. (°C):
4 Pictures:
 References:
1) Hanada, T., et al., J. Biol. Chem. 282, 37298-37302 (2007) Reactivity:
This antibody reacts with Atg5-Atg12 complex (55 kDa) on Western blotting.
Intended Use:
For Research use only. Not for use in diagnostic procedure. |
