Angiogenesis
Apoptosis
Autophagy & Proteolysis
Cancer & Cell Proliferation
Cell Surface Antigens
Cellular Stress
Cytokines & Growth Factors
Epigenetics
Epitope Tags
Fluorescent Proteins
GPCR
In Vitro Diagnostics
Inflammation & Immunology
Metabolism
Molecular Biology
Neuroscience
Signal Transduction
Solute Carrier
Virology
Other
Product Catalog |
Phospho Histone H3(Ser28) Polyclonal AntibodyCode No: PM006
Target:
H3 (Ser28) Background:
The nucleosome is made up of four core histone proteins (H2A, H2B, H3, and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multIPPle different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. The role of histone variants, and specially those of H3 and H2A, in various nuclear processes has been long appreciated. Phosphorylation of Histone H3 at serines 10 and 28 has been linked to various environmental stress stimuli and specific chromatin structure.
Size:
50 µg
Application:
WB
Application:
IC
Clone Number:
polyclonal
Product Type:
Primary Antibody Epitope:
This antibody detects 15-17 kDa of phosphorylated Histone H3 (Ser28) on Western blotting and Immunocytochemistry.
Host Species:
Rabbit
Species Reactivities:
Species Reactivities
Isotype:
IgG (aff.)
Storage Temp. (°C):
-20
Shipping Temp. (°C):
4 Pictures:
 References:
1) Sasagawa, Y., et al., Genes Cells 8, 857-872 (2003) Formulation:
100 L volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Intended Use:
For Research use only. Not for use in diagnostic procedure. |
