Atg14
Code No: PD026
Datasheet:
FID:7083 | PATH:sites/default/files/datasheets/PD026.PDF
Background:
Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Mammalian homologues of Atg14/Atg14L/BARKOR localizes on the isolation membrane and autophagosome, and it necessary for autophagosome formation. Atg14 binds to the PI3K complex (Beclin-1, Vps34, Vps15) and promotes the autophagosome formation.
Product Type:
Primary Antibody
Species Reactivities:
Human
Species Reactivities:
Mouse
Species Reactivities:
Rat
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References:
1) Matsunaga, K., et al., Nat. Cell Biol. 11, 385-396 (2009)
2) Zhong, Y., et al., Nat. Cell Biol. 11, 468-476 (2009)
3) Itakura, E., et al., Mol. Biol. Cell 19, 5360-5372 (2008)
4) Sun, Q., et al., PNAS 105, 19211-19216 (2008)
Reactivity:
This antibody reacts with human, mouse and rat Atg14 on Western blotting and Immunoprecipitation.
Intended Use:
For Research use only. Not for use in diagnostic procedure.
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