| Background: | Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Beclin 1, the mammalian homologue of yeast Atg6, was first identified Bcl-2-interacting protein. Beclin 1 localizes to the trans-Golgi network, and forms a complex with phosphatidylinositol 3-kinase. Beclin 1 is essential for early autophagosome formation. |
| Clonality: | Polyclonal |
| Formulation: | In PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 8678 |
| Gene ID Mouse: | 56208 |
| Host Species: | Rabbit |
| Immunogen: | Recombinant Human fulll length Beclin 1 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 ug |
| Species Reactivities: | Human, Mouse, Rat, Hamster |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Beclin 1 |
Applications: IC, IP, WB
| ICC: | 1:100 |
| IPP: | 2.5 μL/200 μL of cell extract from 5x106 |
| WB: | 1:1000 |
There are no references for Anti-Beclin 1 pAb at this time.
