Solutions for Life Science & Diagnostics
Anti-SET β (p41) (Caspase-7 activation state antibody) (Human) pAb
Additional Information
Anti-SET β (p41) (Caspase-7 activation state antibody) (Human) pAb Specifications
| Background: | Cyclin D1, also known as Bcl-1, CCND1, or PRAD1, is a 36 kDa nuclear protein that plays a key regulatory role during the G1 phase of the cell cycle by regulating the activity of Cdk proteins. Cyclin D1 forms a complex with Cdk4, then binds to and phosphorylates Rb protein, triggering cells to progress from G0/G1 to S and thus driving cellular proliferation. Cyclin D1 protein overexpression is found in the majority of human breast cancers and is usually linked with poor prognosis. Overexpression of cyclin D1 is a well-established criterion for the diagnosis of Mantle Cell Lymphoma, and also has been used to distinguish malignant breast carcinomas from premalignant breast lesions. |
| Clonality: | Polyclonal |
| Formulation: | In PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 6418 |
| Gene ID Mouse: | 56086 |
| Host Species: | Rabbit |
| Immunogen: | synthetic peptide Ac-GADETSEKEQC (Human SETbeta, 19-28 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 50 µg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | SET beta |
Applications: IC, IP, WB
| ICC: | 1:50 |
| IPP: | 2 ug/250 uL of cell extract from 5x106 |
| WB: | 1:5,000 (for chemiluminescence detection system) |
There are no references for Anti-SET β (p41) (Caspase-7 activation state antibody) (Human) pAb at this time.
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