Anti-SET β (p42) (Human) pAb
Anti-SET β (p42) (Human) pAb Specifications
|Background:||Cyclin D1, also known as Bcl-1, CCND1, or PRAD1, is a 36 kDa nuclear protein that plays a key regulatory role during the G1 phase of the cell cycle by regulating the activity of Cdk proteins. Cyclin D1 forms a complex with Cdk4, then binds to and phosphorylates Rb protein, triggering cells to progress from G0/G1 to S and thus driving cellular proliferation. Cyclin D1 protein overexpression is found in the majority of human breast cancers and is usually linked with poor prognosis. Overexpression of cyclin D1 is a well-established criterion for the diagnosis of Mantle Cell Lymphoma, and also has been used to distinguish malignant breast carcinomas from premalignant breast lesions.
|Formulation:||In PBS/50% glycerol, pH 7.2|
|Gene ID Human:||6418|
|Gene ID Mouse:||56086|
|Immunogen:||synthetic peptide Ac-APAAKVSKKELNC (Human SETbeta, 3-14 a.a.)|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
Applications: IC, IP, WB
|IPP:||1 μg/250 μL of cell extract from 5x106 |
There are no references for Anti-SET β (p42) (Human) pAb at this time.