| Alternative Names: | Fas (TNF receptor superfamily, member 6) |
| Background: | It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas (also known as CD95/APO-1) is a cell surface protein belonging to the tumor necrosis factor receptor superfamily, which is expressed in a variety of normal and neoplastic cells. Binding of FasL to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies results in rapid induction of apoptosis in Fas expressing cells. Clone ZB4 is known as Fas blocking, Fas neutralizing or Fas antagonistic antibody, whereas anti-human Fas antibody (clone CH-11) is known as the agonistic antibody. |
| Clonality: | Monoclonal |
| Clone Number: | ZB4 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol , pH 7.2 |
| Gene ID Human: | 355 |
| Gene ID Mouse: | 14102 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human Fas |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Fas |
Applications: FCM, NT, WB
| FCM: | 5-20 ug/mL (final concentration) |
| NT: | 10-500 ng/mL |
| WB: | 5 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-Fas (CD95) (Human) mAb at this time.
