Alexa Fluor®488-anti-Fas/CD95 Monoclonal Antibody

Datasheet:

MD-10-A48_ver1.pdf

( Email this file )

Gene/antigen ID number:

355

Target:

Fas/CD95

Background:

It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has structural homology with a number of cell-surface receptors, including tumor necrosis factor receptor and nerve growth factor receptor.

Size:

100 µL

Application:

FCM

Clone Number:

UB2

Conjugate:

Agarose

Product Type:

Primary Antibody

Host Species:

Mouse

Species Reactivities:

Human

Isotype:

IgG1

Storage Temp. (°C):

4

Pictures:

Alexa Fluor®488-anti-Fas/CD95 Monoclonal Antibody

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References:

1) Boula, A., et al., Clin. Cancer Res. 12, 3099-3108 (2006)
2) Vega, M. I., et al., J. Immunol. 175, 2174-2183 (2005)
3) Mezosi, E., et al., Mol. Endocrinol 19, 804-811(2005)
4) Hauptschein, R., et al., Cancer Res.65, 1887-1896 (2005)
5) Suhara, T., et al., Hypertension 43, 1208-1213 (2004)
6) Suhara, T., et al., Mol. Cell. Biol. 22, 680-691 (2002)
7) Shinohara, H., et al., Cancer Res. 60, 1766-1772 (2000)
8) Sata, M., et al., Arterioscler. Thromb. Vasc. Biool. 20, 309-316 (2000)
9) Hiromatsu, Y., et al., J. Clin. Endocrinol. Metab. 84, 2896-2902 (1999)
10) Kuwano, K., et al., Am. J. Respir. Cell Mol. Biol. 20, 53-60 (1999)
11) Dai, C. H., et al., Blood 91, 1235-1242 (1998)
12) Ando, K., et al., J. Immunol. 158, 5283-5291 (1997)
13) Boirivant, M., et al., J. Clin. Invest. 98, 2616-2622 (1996)
14) Hata, H., et al., Blood 86, 1939-1945 (1995)
15) Watanabe-Fukunaga, R., Nature 356, 314-317 (1992)
16) Ito, N., et al., Cell. 66, 233-243 (1991)
17) Kobayashi, N., et al., PNAS. 87, 9620-9624 (1990)
18) Yonehara, S., et al., J. Exp.Med. 169, 1747-1756 (1989)

Reactivity:

This antibody recognizes the human Fas antigen specifically. Clone UB2 does not recognize the mouse Fas antigen.

Intended Use:

For Research use only. Not for use in diagnostic procedure.

Product Catalog

Alexa Fluor®488-anti-Fas/CD95 Monoclonal Antibody

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