Solutions for Life Science & Diagnostics
Anti-PI-3 Kinase (p85α) (Human) mAb
Additional Information
Anti-PI-3 Kinase (p85α) (Human) mAb Specifications
| Alternative Names: | PIK3R1; phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| Background: | Phosphoinositide 3-kinase (PI3K) family of enzymes generate 3-phosphorylated phosphoinositides that act as second messengers downstream of numerous cellular receptors. This family control several cellular responses including cell growth, survival cytoskeletal remodeling and the trafficking of intracellular organelles in many different cell types. There are four subgroups (class IA, IB, II, III) of PI3K with distinct structure and substrate specificity. Class IA PI3K, which function downstream of activated tyrosine kinases, are heterodimers composed of a p110 catalytic subunit (a, b, or o) and a tightly associated regulatory subunit (p85a, p55a, p50a, p85B, or p55y). Each regulatory subunit can interchangeably associate with different catalytic subunits and shows a unique tissue distribution. p85a is the major regulatory subunit of class IA PI3Ks in most types of cells including immune cells. |
| Clonality: | Monoclonal |
| Clone Number: | AB6 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 5266 |
| Gene ID Mouse: | 20702 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human p85α |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 k |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | PI-3 |
Applications: IC, IP, WB
| ICC: | 10 μg/mL |
| IPP: | 1-5 μg/600 μL of cell extract from 5x106 |
| WB: | 1 μg/mL |
There are no references for Anti-PI-3 Kinase (p85α) (Human) mAb at this time.
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