Anti-EEA1 monoclonal anitbody(clone:3C10)
Code No: M176-3
Datasheet:
FID:11639 | PATH:sites/default/files/datasheets/M176-3_ver1.pdf
Background:
The early endosome is a cellular compartment inside eukaryotic cells. It is receiving endocytosed material and sorting them for vesicular transport to late endosomes and lysosomes or for recycling to the plasma membrane. EEA1 (Early Endosome Antigen1) is a 170 kDa coiled-coil protein, which is required for vesicular transport of proteins through early endosomes. It binds membrane lipids through its FYVE domain.
Product Type:
Primary Antibody
Species Reactivities:
Human
Species Reactivities:
Mouse
Species Reactivities:
Rat
References:
1) Gaullier, J. M., et al., J. Biol. Chem. 275, 24595-24600 (2000)
2) Mu, F. T., et al., J. Biol. Chem. 270, 13503-13511 (1995)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
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