| Background: | Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells. |
| Clonality: | Monoclonal |
| Clone Number: | N43-7 |
| Conjugate: | Alexa Fluor® 647 |
| Formulation: | 1 mg/mL in PBS/1% BSA/0.09% sodium azide |
| Gene ID Human: | 8829 |
| Gene ID Mouse: | 18186 |
| Host Species: | Rat |
| Immunogen: | Recombinant Mouse Neuropilin-1 (1-856 aa) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a κ |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | Neuropilin-1/CD304 |
Applications: FCM
| FCM: | 1 μg/mL |
There are no references for Anti-Neuropilin-1 (CD304) (Mouse) mAb-Alexa Fluor® 647 at this time.