p62/SQSTM1 monoclonal anitbody(clone:5F2) : Trial Size

Datasheet:

Target:

p62/SQSTM1

Background:

p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein directly interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency.

Size:

10 μg

Application:

IC

Application:

IPP

Application:

IHC

Application:

WB

Clone Number:

5F2

Product Type:

Primary Antibody

Host Species:

Mouse

Species Reactivities:

Human

Storage Temp. (°C):

-20

Shipping Temp. (°C):

4

Related Products:

PM045 anti-p62/SQSTMS (polyclonal)
PD014 anti-LC3 (polyclonal) (for WB)
PD015 anti-LC3 (polyclonal) (for IC)
PM036 anti-LC3 (polyclonal) (for WB, IP, IC, IHC)
M115-3 anti-LC3 (51-11) (for WB)
M152-3 anti-LC3 (4E12) (for WB, IP, IC)
PM034 anti-Atg3 (polyclonal)
M133-3 anti-Atg3 (3E8)
M134-3 anti-Atg4B (9H5)
PM039 anti-Atg7 (polyclonal)
M151-3 anti-Atg10 (5A7)
PM040 anti-Atg16L (polyclonal)
M150-3 anti-Atg16L (1F12)
M135-3 anti-GABARAP (1F4)
PM037 anti-GABARAP (polyclonal)
PM038 anti-GATE-16 (polyclonal)
PM036-P Positive control for anti-LC3 antibody

References:

1) Ichimura, Y., et al., J. Biol. Chem. 283, 22847-22857 (2008)
2) Komatsu, M., et al., Cell 131, 1149-1163 (2007)

Reactivity:

This antibody reacts with human p62 on Western blotting, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry.

Intended Use:

For Research use only. Not for use in diagnostic procedure.

Product Catalog

p62/SQSTM1 monoclonal anitbody(clone:5F2) : Trial Size

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