| Background: | p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein directly interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency. |
| Gene ID Human: | 8878 |
| Gene ID Mouse: | 18412 |
| Host Species: | Mouse |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 10 μg |
| Status: | RUO |
| Storage: | -20 |
| Target: | p62/SQSTM1 |
Applications:
There are no references for p62/SQSTM1 monoclonal anitbody(clone:5F2) : Trial Size at this time.