Angiogenesis
Apoptosis
Autophagy & Proteolysis
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Cell Surface Antigens
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Product Catalog |
Atg5 monoclonal anitbody(clone:4D3) : Trial SizeCode No: M153-3B
Target:
Atg5 Background:
Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg12-Atg5-Atg16L forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane.
Size:
10 μg
Application:
WB
Clone Number:
4D3
Product Type:
Primary Antibody
Host Species:
Mouse
Species Reactivities:
Human
Species Reactivities:
Mouse
Species Reactivities:
Hamster
Isotype:
IgG1 k
Storage Temp. (°C):
-20
Shipping Temp. (°C):
4 Pictures:
 References:
1) Hanada, T., et al., J. Biol. Chem. 282, 37298-37302 (2007) Reactivity:
This antibody reacts with Atg5-Atg12 complex (55 kDa) on Western blotting. Not react with monomeric Atg5.
Intended Use:
For Research use only. Not for use in diagnostic procedure. |
