| Background: | Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates. |
| Clonality: | Monoclonal |
| Clone Number: | 1D11 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 55143 |
| Gene ID Mouse: | 52276 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human fulll length Borealin |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Borealin |
Applications: IC, IP, WB
| ICC: | 1-5 μg/mL |
| IPP: | 1 μg/50 μL of cell extract from 1 x 106 |
| WB: | 1 μg/mL |
There are no references for Anti-Borealin (Human) mAb at this time.
