| Background: | KIF11 (Eg5), a member of kinesin superfamily, is a tetrameric motor protein that is phosphorylated specifically during mitosis by cdc2/cyclin B kinase at Thr927. It is essential to forming bipolar spindles needed to divide sister chromatids, inhibition of KIF11 arrests HeLa cells at mitosis with monoaster state. |
| Clonality: | Monoclonal |
| Clone Number: | 2A5 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 3832 |
| Gene ID Mouse: | 16551 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human fulll length KIF11 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2b |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | KIF11 |
Applications: IC, IP
| ICC: | 5 μg/mL |
| IPP: | 1 μg/50 μL of cell extract from 5 x 106 cells |
There are no references for Anti-KIF11 (Human) mAb at this time.