Solutions for Life Science & Diagnostics
Anti-Foxp3 (Human) mAb
Additional Information
Anti-Foxp3 (Human) mAb Specifications
| Background: | Forkhead-winged helix P3 (Foxp3), also known as Scurfin or JM2, is a 50-55 kDa transcrIPPtion factor, originally identified as the gene defective in Scurfy mice. Scurfy mice and humans with similar mutations spontaneously develop autoimmune diseases (IPPEX). Resent reports revealed that Foxp3 is expressed in CD4+ CD25+ regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4+ Foxp3-T cells induced a Treg-like phenotype in these cells. Importantly, these reports indicate that Foxp3 is a specific marker for Treg cells. Taken together, Foxp3 is believed to be a crucial regulator of the development and function of Treg cells. |
| Clonality: | Monoclonal |
| Clone Number: | 99D04 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 50943 |
| Gene ID Mouse: | 20371 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human Foxp3 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Foxp3 |
Applications: IC, IH, IP, WB
| ICC: | 10 ug/mL |
| IHC: | 10 ug/mL (Heat treatment is necessary for paraffin |
| IPP: | 5 ug/100 uL of cell extract from 2x106 cells |
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-Foxp3 (Human) mAb at this time.
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