Solutions for Life Science & Diagnostics
Anti-TRAF1 (Mouse) mAb
Additional Information
Anti-TRAF1 (Mouse) mAb Specifications
| Background: | Tumor necrosis factor receptor (TNF-R) superfamily such as TNFR1, TNFR2, CD30 and CD40-mediated signaling is provided by the TRAF (TNF receptor associated factors) family. The members of the TRAF family form either homodimers or heterodimers result in extensive diversity and specificity in their signal transduction pathways. TRAF1 and TRAF2 were found to associate with the cytoplasmic domains of the TNFR2. However, TRAF1 is indirectly associated TNFR2 via dimerization with TRAF2. TRAF1 and TRAF2 bind independently to the same region of CD30. Both TRAF1 and TRAF2 interact strongly with A20, a TRAF2-mediated NF-ï«B activation indirectly through the formation of a TRAF2-TRAF1-A20 complex. |
| Clonality: | Monoclonal |
| Clone Number: | 3D4 |
| Formulation: | 1.0 mg/mL in PBS /50% glycerol, pH 7.2 |
| Gene ID Human: | 7185 |
| Gene ID Mouse: | 22029 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Mouse fulll length TRAF1 (1-410 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 k |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | TRAF1 |
Applications: WB
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-TRAF1 (Mouse) mAb at this time.
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