Solutions for Life Science & Diagnostics
Anti-Neuropsin (Mouse) mAb
Additional Information
Anti-Neuropsin (Mouse) mAb Specifications
| Background: | Neuropsin is a trypsin-type, extracellular, serine protease that was first cloned from mouse limbic brain as a factor related to neural plasticity. Physiological studies indicated that kindling stimulation induced neuropsin mRNA and its protease activity also increased in limbic areas during kindling and long-term potentiation. Subsequent study indicated that neuropsin mRNA localized not only in the limbic brain, but also in developing organs and adult keratinocytes. Recent immunohistochemical analysis demonstrated that neuropsin localized exclusively in the keratinizing epithelia of the epidermis and various stratified mucous membranes. During development, neuropsin was found in the various epithelia at embryonic days 14.5-15.5, prior to formation of the stratum corneum. Much stronger expression of neuropsin in nude mouse skin and mucous membranes than in normal mice. Those studies suggested that neuropsin is related to differentiation of keratinocytes and the process of keratogenesis. |
| Clonality: | Monoclonal |
| Clone Number: | MabF12 |
| Formulation: | This antibody is lyophilized form. Prepare a stock solution by dissolving the lyophilized antibody with 100 mL of distilled water. After reconstitution, IgG concentration should be 1 mg/mL in PBS (pH 7.2)/1% Sucrose. No preservative is contained. |
| Gene ID Human: | 221391 |
| Gene ID Mouse: | 353344 |
| Host Species: | Rat |
| Immunogen: | Recombinant |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | Neuropsin |
Applications: IH, IP, WB
| IHC: | Optimal Dilution to be determined by end user. |
| IPP: | Optimal Dilution to be determined by end user. |
| WB: | 1 μg/mL |
There are no references for Anti-Neuropsin (Mouse) mAb at this time.
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