| Alternative Names: | thioredoxin interacting protein |
| Background: | Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that Txnip plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation. |
| Clonality: | Monoclonal |
| Clone Number: | JY2 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 10628 |
| Gene ID Mouse: | 56338 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human Txnip/VDUP1 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | VDUP-1/Txnip |
Applications: IH, IP, WB
| IHC: | Reference 1 |
| IPP: | 2 μg/200 μL of cell extract from 5x106 |
| WB: | 1 μg/mL |
There are no references for Anti-Txnip (VDUP1) (Human) mAb at this time.