Solutions for Life Science & Diagnostics
Anti-14-3-3 γ (Human) mAb
Additional Information
Anti-14-3-3 γ (Human) mAb Specifications
| Background: | The 14-3-3 protein family comprises critical regulatory molecules involved in signaling during cell division, proliferation, and apoptosis. 14-3-3ï§, a subtype of the 14-3-3 family of proteins, was thought to be brain- and neuron-specific. However, 14-3-3ï§ was not neuron-specific but also expressed in astrocytes. Endogenous 14-3-3ï§ proteins in immature astrocytes appeared filamentous and co-localized with filamentous actin (F-actin). And, 14-3-3ï§ proteins play a role in cytoskeletal function during the process of cell division and apoptosis in astrocytes in association with actin. This expression is induced in arterial trauma by cytokines, and suggests that this protein may play an important role in progression of vascular proliferative diseases. |
| Clonality: | Monoclonal |
| Clone Number: | KC21 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 7532 |
| Gene ID Mouse: | 22628 |
| Host Species: | Mouse |
| Immunogen: | KLH-Human 14-3-3gammmaN-terminal peptide (1-12 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | 14-3-3 Gamma |
Applications: IP, WB
| IPP: | 2 ug/100 ug of cell extract from 5x106 |
| WB: | 0.1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-14-3-3 γ (Human) mAb at this time.
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