Solutions for Life Science & Diagnostics
Anti-Nestin (Human) mAb
Additional Information
Anti-Nestin (Human) mAb Specifications
| Background: | Nestin is a large (220~240kDa) Class VI intermediate filament that is abundantly expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments. Since nestin is absent from nearly all mature CNS cells, it is commonly used as a marker for neuronal stem cells. Nestin is also expressed in gliomas, melanoma, and tumor endothelial cells, making it an excellent angiogenic marker to evaluate neovascularity of endothelial cells in tumors. |
| Clonality: | Monoclonal |
| Clone Number: | 10C2 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 10763 |
| Gene ID Mouse: | 18008 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human fulll length Nestin |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Nestin |
Applications: FCM, IH, WB
| FCM: | 10 ug/mL (final concentration) |
| IHC: | 10 ug/mL (Heat treatment is necessary for paraffin |
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-Nestin (Human) mAb at this time.
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