Solutions for Life Science & Diagnostics
Anti-SREBP (Human) mAb
Additional Information
Anti-SREBP (Human) mAb Specifications
| Background: | Sterol regulatory binding proteins (SREBP) are membrane-bound transcription factors that regulate cholesterol and fatty acid homeostasis. SREBP proteins are key transcriptional regulators of triglyceride synthesis and lipogenic enzymes such as fatty acid synthase. SREBP-1a and SREBP-1c are derived from the same gene by alternative splicing, but they appear to have distinct roles in adipocyte fat metabolism. Overexpression of SREBP-1a results in greatly increased rates of fatty acid synthesis and enhanced fatty acid secretion, while overexpression of SREBP-1c inhibits adipocyte differentiation, causing diabetes and a loss of white adipose tissue. |
| Clonality: | Monoclonal |
| Clone Number: | 2A4 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH7.2 |
| Gene ID Human: | 6720 |
| Gene ID Mouse: | 20787 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human SREBP-1 (301-407 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | SREBP-1 |
Applications: IP, WB
| IPP: | 10 ug/200 uL of cell extract from 5x106 |
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-SREBP (Human) mAb at this time.
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