Anti-CENP-E (Human) mAb
Anti-CENP-E (Human) mAb Specifications
|Background:||Centromere protein-E (CENP-E) is a kinesin-like protein that binds to kinetochores during mitosis. CENP-E is required for full chromosome alignment and normal progression through mitosis. CENP-E is essential for stable, bioriented attachment of chromosomes to spindle microtubules, for development of tension across aligned chromosomes, for stabilization of spindle poles, and for satisfying the mitotic checkpoint. The localization of CENP-E differs markedly from other centromere proteins, CENP-A, CENP-B, CENP-C and CENP-D. In contrast to these antigens, CENP-E expression is appeared at the centromere region of chromosomes during prometaphase but is not detected during interphase.
|Formulation:||1.0 mg/mL in PBS/50% glycerol, pH 7.2|
|Gene ID Human:||1062|
|Gene ID Mouse:||229841|
|Immunogen:||Recombinant fulll length Human CENP-E|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
There are no references for Anti-CENP-E (Human) mAb at this time.