Solutions for Life Science & Diagnostics
Anti-MAD2 (Human) mAb
Additional Information
Anti-MAD2 (Human) mAb Specifications
| Alternative Names: | MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast) |
| Background: | Some of the spindle checkpoint components are evolutionarily conserved from yeast to human. They include mitotic arrest deficiency 1 (MAD1), MAD2, MAD3/BUBR1, budding uninhibited by benomyl 1 (BUB1), BUB3, and monopolar spindle 1 (MPS1). MAD1 interacts with several checkpoint proteins, forming a complex with MAD2 and recruiting MAD2 to unattached kinetochores. MAD1 and Cdc20 can bind MAD2, but these two bindings are exclusive. They share a 10-residue MAD2-binding motif. It has been suggested that MAD1 acts as a positive regulator and a competitive inhibitor of the MAD2-Cdc20 complex. |
| Clonality: | Monoclonal |
| Clone Number: | 2G9 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH7.2 |
| Gene ID Human: | 4085 |
| Gene ID Mouse: | 56150 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human MAD2 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | MAD-2 |
Applications: IP, WB
| IPP: | 2 ug/200 uL of cell extract from 5x106 |
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-MAD2 (Human) mAb at this time.
Product Images
