Solutions for Life Science & Diagnostics
Anti-DNA Polymerase δ p125 Catalytic Subunit (Human) mAb
Additional Information
Anti-DNA Polymerase δ p125 Catalytic Subunit (Human) mAb Specifications
| Background: | In eukaryotic cells, 3 types of DNA polymerases (pol), pol ï¡, pol ï¤ and pol ï¥ function in accurate and efficient DNA replication. Pol ï¤ is a heteromultimeric enzyme composed of a 125 kDa major catalytic subunit and three smaller accessory subunits. Pol ï¤ requires a number of accessory molecules to exert its full activity. Proliferating cell nuclear antigen (PCNA) forms a doughnut-shaped trimer with a 35 Ã… hole and works as the sliding clamp and replication factor C acts as the clamp loader to improve Pol ï¤ processivity. Pol ï¤ is also involved in nucleotide excision repair of DNA. |
| Clonality: | Monoclonal |
| Clone Number: | 5G1 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 11196 |
| Gene ID Mouse: | 207352 |
| Host Species: | Rat |
| Immunogen: | Recombinant fulll length Human p125 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Source: | This antibody was purified from hybridoma (clone 5G1) supernatant using protein G agarose. This hybridoma was established by fusion of mouse myeloma cell P3-X63-Ag8-653 with Lou/c rat splenocyte immunized with recombinant full length His- human p125. |
| Species Reactivities: | Human, Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | delta p125 |
Applications: WB
| WB: | 0.1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-DNA Polymerase δ p125 Catalytic Subunit (Human) mAb at this time.
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