Anti-Synaptojanin (Rat) mAb
Anti-Synaptojanin (Rat) mAb Specifications
|Background:||Inositol polyphosphate 5-phospha- tases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which function as second messengers to regulate events at cell membranes, such as membrane trafficking and cell morphology. Synaptojanin 1 is a phosphoinositide (PI) phosphatase that selectively removes the 3-, 4-, and 5-phosphates from PIs. Two splice variants of synaptojanin 1 include a 170 kDa that is widely expressed in non-neuronal cells and a 145 kDa form that is found only in adult brain. Synaptojanin is the only other major brain protein besides dynamin that binds the SH3 domain of amphIPPhysin, suggesting a role for synaptojanin in endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.
|Formulation:||1.0 mg/mL in PBS/50% glycerol, pH 7.2|
|Gene ID Human:||8867|
|Gene ID Mouse:||104015|
|Immunogen:||Recombinant RatSynaptojanin (1156-1286 a.a.)|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
|Species Reactivities:||Mouse, Rat|
|WB:||1-5 ug/mL (for chemiluminescence detection system)|
There are no references for Anti-Synaptojanin (Rat) mAb at this time.