Solutions for Life Science & Diagnostics
Anti-Synaptojanin (Rat) mAb
Additional Information
Anti-Synaptojanin (Rat) mAb Specifications
| Background: | Inositol polyphosphate 5-phospha- tases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which function as second messengers to regulate events at cell membranes, such as membrane trafficking and cell morphology. Synaptojanin 1 is a phosphoinositide (PI) phosphatase that selectively removes the 3-, 4-, and 5-phosphates from PIs. Two splice variants of synaptojanin 1 include a 170 kDa that is widely expressed in non-neuronal cells and a 145 kDa form that is found only in adult brain. Synaptojanin is the only other major brain protein besides dynamin that binds the SH3 domain of amphIPPhysin, suggesting a role for synaptojanin in endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton. |
| Clonality: | Monoclonal |
| Clone Number: | 5H1 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 8867 |
| Gene ID Mouse: | 104015 |
| Host Species: | Mouse |
| Immunogen: | Recombinant RatSynaptojanin (1156-1286 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Synaptojanin |
Applications: WB
| WB: | 1-5 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-Synaptojanin (Rat) mAb at this time.
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