Solutions for Life Science & Diagnostics
Anti-CD177 (Human) mAb
Additional Information
Anti-CD177 (Human) mAb Specifications
| Background: | CD177, also known as neutrophil-specific antigen (NB1) and human neutrophil antigen (HNA-2a), is a 58-64 kDa GPI-anchored glycoprotein (49-55 kDa under reducing conditions) located on plasma membranes and secondary granules of a distinct subset of neutrophils. CD177 is expressed on 55 to 64% of neutrophils and neutrophilic myelocytes in healthy individuals. The expression of CD177 is upregulated on granulocytes stimulated with the chemotactic peptide fMLP. The function of CD177 is unknown, but it was first identified in sera from women alloimmunized during pregnancy, and antibodies against CD177 can be involved in neonatal alloimmune neutropenia. |
| Clonality: | Monoclonal |
| Clone Number: | MEM-166 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH7.2 |
| Gene ID Human: | 57126 |
| Gene ID Mouse: | 68891 |
| Host Species: | Mouse |
| Immunogen: | human granulocytes |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | CD177 |
Applications: FCM, WB
| FCM: | 1-10 ug/mL (final concentration) |
| WB: | 10 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-CD177 (Human) mAb at this time.
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